help button home button JAMIA Bigger figures
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

First published March 31, 2005 as JAMIA PrePrint; doi:10.1197/jamia.M1740
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
M1740v1
12/4/377    most recent
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Horsky, J.
Right arrow Articles by Patel, V. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Horsky, J.
Right arrow Articles by Patel, V. L.
J Am Med Inform Assoc. 2005;12:377-382. DOI 10.1197/jamia.M1740.
© 2005 American Medical Informatics Association


Case Report

Comprehensive Analysis of a Medication Dosing Error Related to CPOE

Jan Horsky, MA, Mphil, Gilad J. Kuperman, MD, PhD and Vimla L. Patel, PhD, DSc

Affiliations of the authors: Laboratory of Decision Making and Cognition (JH, VLP), Department of Biomedical Informatics (JH, GJK, VLP), Columbia University; Department of Clinical Practice Evaluation, NewYork-Presbyterian Hospital (GJK), New York, NY.

Correspondence and reprints: Jan Horsky, MA, MPhil, Department of Biomedical Informatics, Columbia University, 622 West 168th Street, Vanderbilt Clinic, 5th Floor, New York, NY 10032-3720; e-mail: <horsky{at}dbmi.columbia.edu>.

Received for publication: 11/12/04; accepted for publication: 02/21/05.

This case study of a serious medication error demonstrates the necessity of a comprehensive methodology for the analysis of failures in interaction between humans and information systems. The authors used a novel approach to analyze a dosing error related to computer-based ordering of potassium chloride (KCl). The method included a chronological reconstruction of events and their interdependencies from provider order entry usage logs, semistructured interviews with involved clinicians, and interface usability inspection of the ordering system. Information collected from all sources was compared and evaluated to understand how the error evolved and propagated through the system. In this case, the error was the product of faults in interaction among human and system agents that methods limited in scope to their distinct analytical domains would not identify. The authors characterized errors in several converging aspects of the drug ordering process: confusing on-screen laboratory results review, system usability difficulties, user training problems, and suboptimal clinical system safeguards that all contributed to a serious dosing error. The results of the authors' analysis were used to formulate specific recommendations for interface layout and functionality modifications, suggest new user alerts, propose changes to user training, and address error-prone steps of the KCl ordering process to reduce the risk of future medication dosing errors.




This article has been cited by other articles:


Home page
PediatricsHome page
J. A. Taylor, L. A. Loan, J. Kamara, S. Blackburn, and D. Whitney
Medication Administration Variances Before and After Implementation of Computerized Physician Order Entry in a Neonatal Intensive Care Unit
Pediatrics, January 1, 2008; 121(1): 123 - 128.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Med. Inform. Assoc.Home page
F. FitzHenry, J. F. Peterson, M. Arrieta, L. R. Waitman, J. S. Schildcrout, and R. A. Miller
Medication Administration Discrepancies Persist Despite Electronic Ordering
J. Am. Med. Inform. Assoc., November 1, 2007; 14(6): 756 - 764.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Med. Inform. Assoc.Home page
S. Eslami, A. Abu-Hanna, and N. F. de Keizer
Evaluation of Outpatient Computerized Physician Medication Order Entry Systems: A Systematic Review
J. Am. Med. Inform. Assoc., July 1, 2007; 14(4): 400 - 406.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Med. Inform. Assoc.Home page
E. M. Campbell, D. F. Sittig, J. S. Ash, K. P. Guappone, and R. H. Dykstra
Types of Unintended Consequences Related to Computerized Provider Order Entry
J. Am. Med. Inform. Assoc., September 1, 2006; 13(5): 547 - 556.
[Abstract] [Full Text] [PDF]


Home page
Qual Saf Health CareHome page
H Singh, L A Petersen, and E J Thomas
Understanding diagnostic errors in medicine: a lesson from aviation.
Qual. Saf. Health Care, June 1, 2006; 15(3): 159 - 164.
[Abstract] [Full Text] [PDF]


Home page
ANN INTERN MEDHome page
C. J. McDonald
Computerization Can Create Safety Hazards: A Bar-Coding Near Miss
Ann Intern Med, April 4, 2006; 144(7): 510 - 516.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Med. Inform. Assoc.Home page
R. A. Miller, R. M. Gardner, K. B. Johnson, and G. Hripcsak
Clinical Decision Support and Electronic Prescribing Systems: A Time for Responsible Thought and Action
J. Am. Med. Inform. Assoc., July 1, 2005; 12(4): 403 - 409.
[Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the American Medical Informatics Association.