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First published December 15, 2005 as JAMIA PrePrint; doi:10.1197/jamia.M1656
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J Am Med Inform Assoc. 2006;13:188-196. DOI 10.1197/jamia.M1656.
© 2006 American Medical Informatics Association


Research Paper

Integrating "Best of Care" Protocols into Clinicians' Workflow via Care Provider Order Entry: Impact on Quality-of-Care Indicators for Acute Myocardial Infarction

Asli Ozdas, PhD, Theodore Speroff, PhD, L. Russell Waitman, PhD, Judy Ozbolt, PhD, Javed Butler, MD and Randolph A. Miller, MD

Affiliations of the authors: Department of Biomedical Informatics (AO, LRW, RAM), Department of Medicine, Center for Health Services Research (TS), Division of Cardiology, Department of Medicine (JB), Section of Surgical Sciences (AO), Vanderbilt University, Nashville, TN, Center for Health Services Research, VA Tennessee Valley Healthcare System, Nashville, TN (TS, JB). Institute of Medicine, the National Academies, Washington, DC (JO). Note: JO's participation in this research occurred while she was a faculty member at Vanderbilt University.

Correspondence and reprints: Asli Ozdas, PhD, 2209 Garland Avenue, Nashville, TN 37232; e-mail: <asli.ozdas{at}vanderbilt.edu>.

Received for publication: 07/20/04; accepted for publication: 12/07/05.

Objective: In the context of an inpatient care provider order entry (CPOE) system, to evaluate the impact of a decision support tool on integration of cardiology "best of care" order sets into clinicians' admission workflow, and on quality measures for the management of acute myocardial infarction (AMI) patients.

Design: A before-and-after study of physician orders evaluated (1) per-patient use rates of standardized acute coronary syndrome (ACS) order set and (2) patient-level compliance with two individual recommendations: early aspirin ordering and beta-blocker ordering.

Measurements: The effectiveness of the intervention was evaluated for (1) all patients with ACS (suspected for AMI at the time of admission) (N = 540) and (2) the subset of the ACS patients with confirmed discharge diagnosis of AMI (n = 180) who comprise the recommended target population who should receive aspirin and/or beta-blockers. Compliance rates for use of the ACS order set, aspirin ordering, and beta-blocker ordering were calculated as the percentages of patients who had each action performed within 24 hours of admission.

Results: For all ACS admissions, the decision support tool significantly increased use of the ACS order set (p = 0.009). Use of the ACS order set led, within the first 24 hours of hospitalization, to a significant increase in the number of patients who received aspirin (p = 0.001) and a nonsignificant increase in the number of patients who received beta-blockers (p = 0.07). Results for confirmed AMI cases demonstrated similar increases, but did not reach statistical significance.

Conclusion: The decision support tool increased optional use of the ACS order set, but room for additional improvement exists.




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