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An Integrated Software Suite for Surface-based Analyses of Cerebral Cortex

Affiliation of the authors: Washington University School of Medicine, St. Louis, Missouri.

Correspondence and reprints: David C. Van Essen, PhD, Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 Euclid Avenue, St. Louis, MO 63110; e-mail: vanessen{at}v1.wustl.edu.

Received for publication: 03/16/01; accepted for publication: 05/08/01.

The authors describe and illustrate an integrated trio of software programs for carrying out surface-based analyses of cerebral cortex. The first component of this trio, SureFit (Surface Reconstruction by Filtering and Intensity Transformations), is used primarily for cortical segmentation, volume visualization, surface generation, and the mapping of functional neuroimaging data onto surfaces. The second component, Caret (Computerized Anatomical Reconstruction and Editing Tool Kit), provides a wide range of surface visualization and analysis options as well as capabilities for surface flattening, surface-based deformation, and other surface manipulations. The third component, SuMS (Surface Management System), is a database and associated user interface for surface-related data. It provides for efficient insertion, searching, and extraction of surface and volume data from the database.

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