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First published October 5, 2003 as JAMIA PrePrint; doi:10.1197/jamia.M1399
Journal of the American Medical Informatics Association 2004;11(1):1-10
© 2004 American Medical Informatics Association


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Submitted on May 21, 2003
Accepted on August 5, 2003

The InterMed Approach to Sharable Computer-Interpretable Guidelines: a Review

Mor Peleg1*, Aziz A. Boxwala2, Samson Tu3, Qing Zeng2, Omolola Ogunyemi2, Dongwen Wang4, Vimla L. Patel4, Robert A. Greenes2, and Edward H. Shortliffe4

Affiliation of the authors: 1 Stanford Medical Informatics, Stanford University, Stanford, CA; Current Author Affiliation: Department of Management Information Systems, University of Haifa, Israel, 31905; 2 Decision Systems Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 3 Stanford Medical Informatics, Stanford University, Stanford, CA; 4 Department of Biomedical Informatics, Columbia University, New York, NY

* To whom correspondence should be addressed.

InterMed is a collaboration among research groups from Stanford, Harvard, and Columbia universities. InterMed's primary goal has been to develop a sharable language that could serve as a standard for modeling computer-interpretable guidelines (CIGs). This language, called GuideLine Interchange Format (GLIF), has been developed in a collaborative manner, and in an open process that has welcomed input from the larger community. The goals and experiences of the InterMed project, and lessons that we have learned, may contribute to the work of other researchers who are developing medical knowledge-based tools. The lessons described include: (1) a work process for multi-institutional research and development that considers different viewpoints; (2) an evolutionary lifecycle process for developing medical knowledge representation formats; (3) the role of cognitive methodology to evaluate and assist in the evolutionary development process; development of (4) an architecture and (5) design principles for sharable medical knowledge representation formats; and (6) a process for standardization of a CIG modeling language.




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