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Submitted on January 9, 2004
Accepted on March 14, 2004
Affiliation of the authors: 1 Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center & The University of Cincinnati College of Medicine, Cincinnati, OH; 2 Pharmacy Department, Cincinatti Children's Hospital Medical Center & The University of Cincinnati College of Medicine, Cincinnati, OH
* To whom correspondence should be addressed.
Medication shortages pose serious problems in health care. This study examines the impact of a computer-based reminder in addressing a national methylprednisolone shortage. An alert was designed and implemented in a computerized order entry platform at a children's hospital. The alert informed physicians of the shortage and provided an alternative prescribing pathway. Data regarding the number and type of parenteral corticosteroid prescriptions were collected for a 1-month period before and after the alert was implemented. The alert resulted in a 55% relative reduction in methylprednisolone use and an average reduction of over 3 orders each day. Dexamethasone and hydrocortisone, the recommended alternative medications, increased in use by 12% and 49% respectively. The alert resulted in a $36,552 annualized cost reduction to the institution. Similar alert applications have great potential for effectively altering physician prescribing behavior.
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