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First published April 18, 2006 as JAMIA PrePrint; doi:10.1197/jamia.M2045
Journal of the American Medical Informatics Association 2006;13(4):396-398
© 2006 American Medical Informatics Association

A more recent version of this article appeared on July 1, 2006
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Submitted on January 3, 2006
Accepted on March 26, 2006

Disseminating Drug Prescribing Information: The Cox-2 Inhibitors Withdrawals

Scott M. Strayer MD, MPH1*, David C. Slawson MD1, and Allen F. Shaughnessy PharmD2

Affiliation of the authors: 1 Department of Family Medicine, University of Virginia, Charlottesville, VA ; 2 Tufts University Family Medicine Residency, Tufts University School of Medicine, Boston, MA

* To whom correspondence should be addressed.

This case study examined the recent withdrawal of valdecoxib to determine the timeliness of updates in commonly used information sources used by healthcare professionals. The method included assembling a purposive sample of 15 drug reference and warning systems that were then systematically monitored for several months after the withdrawal of valdecoxib to determine the time to update this information. These information sources were classified and described qualitatively. A time to diffusion curve was plotted and the average number of days to report the drug withdrawal or update reference databases was calculated. Only 2 of 15 information systems reported the drug withdrawal on the actual date of the FDA announcement. Institutional electronic textbooks took an average of 109.8 days (± 14 days) to report the withdrawal. In addition, one web-based resource (PDR.net) and one pharma-sponsored dissemination source (Peerview Press) had not updated their information as of this publication.




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Approaches to Evaluating Electronic Prescribing
J. Am. Med. Inform. Assoc., July 1, 2006; 13(4): 399 - 401.
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