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Submitted on February 16, 2006
Accepted on April 23, 2006
Affiliation of the authors: 1 Biomedical Department of Internal Medicine, University of Palermo, Palermo, Italy ; 2 Clinical Methodology, Epidemiology and Statistics Unit, National Relevance Hospital Trust Civico e Benfratelli, Palermo, Italy
* To whom correspondence should be addressed.
We evaluated the retrieval power of PubMed Clinical Queries, narrow search string, about therapy in comparison with a modified search string to avoid possible retrieval bias. PubMed search strategy was compared to a slight modified string that includes the Britannic English term randomised. We tested the two strings joined onto each of four terms concerning topics of broad interest: hypertension, hepatitis, diabetes, and heart failure. In particular, precision was computed for not-indexed citations. The added word randomised improved total citation retrieval in any case. Total retrieval gain for not-indexed citations ranged from 11.1% to 21.4%. A significant number of RCTs (9.1-18.2%) was retrieved for each of selected topics. They were often recently published RCTs. We think that correction of Clinical Queries filter (when they focus on therapy and use narrow search) is necessary to avoid biased search results with loss of relevant and up-to-date scientifically sound information.
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